Interactions between the 18-wheeler gene and X-chromosome linked genes affect salivary gland development in Drosophila melanogaster

2020-04-24T15:44:54Z (GMT) by Jaquelyn Villalba Elizabeth Eldon
The 18-wheeler (18w) gene found in Drosophila melanogaster directs epithelial cell migration during embryonic development and affects salivary gland morphogenesis. Homozygous 18w mutant embryos have abnormal salivary glands. To identify genes interacting with 18w during epithelial organ development we utilize the observation that embryos heterozygous both for 18w and for a gene that interacts with 18w produce defective salivary glands.