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Expression Pattern in the Developing Zebrafish of the Two Paralogs of Activating Transcription Factor 5 (atf5a and atf5b)

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posted on 20.04.2020 by Roberto Rodriguez-Morales, Gaurav Varshney, Martine Behra


Here we present the expression pattern of two paralogous genes: activating transcription factor 5a (atf5a) and atf5b. We performed whole-mount in situ hybridization using antisense RNA probes to visualize mRNA expression of both genes during larval stages, from 6 hour post-fertilization (hpf) to 5 day post-fertilization. The expression pattern of both genes in brain areas and sensory epithelia will be useful for future knock-out approaches to interrogate the function of each gene in each tissue.

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