10.6084/m9.figshare.12149655.v1
Miwa Wenzel
Miwa
Wenzel
Charles F. Aquadro
Charles F.
Aquadro
The rapidly evolving Drosophila bag-of-marbes gene and its interactions with Wolbachia
TAGC 2020
2020
Drosophila
Bag of Marbles
Wolbachia
Germline Stem Cells
Molecular evolution
Horizontal Gene Transfer
Modeling
Hypomorph
Positive selection
Population, Ecological and Evolutionary Genetics
Host-Parasite Interactions
Genetics
Evolutionary Biology
Developmental Biology
2020-04-20 22:32:50
Poster
https://tagc2020.figshare.com/articles/poster/The_rapidly_evolving_Drosophila_bag-of-marbes_gene_and_its_interactions_with_Wolbachia/12149655
Work on the evolution of the Drosophila bag-of-marbles (bam) gene in the Aquadro lab. Bam plays a key role in early gametogenesis, making it surprising that it shows evidence of rapid and episodic evolution. Here we are exploring they hypothesis that Wolbachia, a germline endosymbiotic bacteria is contributing to bam's rapid evolution. We have discovered a novel interaction between bam and Wolbachia in males; we have created a pipeline to look for the possibility of historic Wolbachia and bam interactions, finding evidence of this in some D. mel individuals; and we have developed two models in which bam and Wolbachia may be interacting, with preliminary results suggesting a model of convergent molecular evolution.