10.6084/m9.figshare.12133263.v1
Aleena Patel
Aleena
Patel
Eyan Yeung
Eyan
Yeung
Sarah McGuire
Sarah
McGuire
Andrew Wu
Andrew
Wu
Jared E Toettcher
Jared
E Toettcher
Stanislav Y Shvartsman
Stanislav
Y Shvartsman
Rebecca D. Burdine
Rebecca
D. Burdine
Transcriptional profiling in zebrafish using optimized photoswitchable MEK
TAGC 2020
2020
optogenetics
ERK pathway
photoswitchable MEK
zebrafish
Developmental Biology
Biological Engineering
2020-04-20 23:48:11
Poster
https://tagc2020.figshare.com/articles/poster/Transcriptional_profiling_in_zebrafish_using_optimized_photoswitchable_MEK/12133263
An optogenetic tool for activating the ERK signaling pathway in vivo in zebrafish is described. The tool is an optimized version of photoswitchable MEK, which we use to investigate the transcriptional effects of ERK activation during germ layer specification.